Kaposi's sarcoma laboratory findings
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [2]Amandeep Singh M.D.[3]
Overview
Overview
Laboratory findings consistent with the diagnosis of Kaposi’s sarcoma include decreased hemoglobin level, positive HIV tests, and positive HHV-8 antigen on immunohistochemistry.
Laboratory Findings
Laboratory Findings
Laboratory findings consistent with the diagnosis of kaposi’s sarcoma include:[1]
Complete blood count
- Decreased hemoglobin level
Electrophoresis
- Detect antibodies against Kaposi sarcoma herpes virus (KSHV) (also known as HHV-8)
ELISA
- Screens for HIV infection among Kaposi’s sarcoma patients
Western Blot
- Confirms HIV infection among Kaposi’s sarcoma patients
Immunohistochemistry
- Kaposi’s sarcoma cells are typically CD34, HHV-8, LANA-1, and D2-40 positive. CD31 and CD34 testing may be useful to assess for vascular origin.
References
References
- ↑ Sarcoma- Kaposi Guide. Cancer.Net (2015) http://www.cancer.net/cancer-types/sarcoma-kaposi/risk-factors-and-prevention Accessed on January, 20 2015
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