Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
LCORL
Introduction
Ligand dependent nuclear receptor corepressor like is a protein that in humans is encoded by the LCORL gene. [1]
Function
Function
This gene encodes a transcription factor that appears to function in spermatogenesis. Polymorphisms in this gene are associated with measures of skeletal frame size and adult height. Alternative splicing results in multiple transcript variants.
References
References
- ↑ “Entrez Gene: Ligand dependent nuclear receptor corepressor like”. Retrieved 2016-11-11.
Further reading
Further reading
- Kunieda T, Park JM, Takeuchi H, Kubo T (2003). “Identification and characterization of Mlr1,2: two mouse homologues of Mblk-1, a transcription factor from the honeybee brain(1)”. FEBS Lett. 535 (1–3): 61–5. doi:10.1016/s0014-5793(02)03858-9. PMID 12560079.
- Sovio U, Bennett AJ, Millwood IY, Molitor J, O’Reilly PF, Timpson NJ, Kaakinen M, Laitinen J, Haukka J, Pillas D, Tzoulaki I, Molitor J, Hoggart C, Coin LJ, Whittaker J, Pouta A, Hartikainen AL, Freimer NB, Widen E, Peltonen L, Elliott P, McCarthy MI, Jarvelin MR (2009). “Genetic determinants of height growth assessed longitudinally from infancy to adulthood in the northern Finland birth cohort 1966”. PLoS Genet. 5 (3): e1000409. doi:10.1371/journal.pgen.1000409. PMCÂ 2646138. PMIDÂ 19266077.
- Soranzo N, Rivadeneira F, Chinappen-Horsley U, Malkina I, Richards JB, Hammond N, Stolk L, Nica A, Inouye M, Hofman A, Stephens J, Wheeler E, Arp P, Gwilliam R, Jhamai PM, Potter S, Chaney A, Ghori MJ, Ravindrarajah R, Ermakov S, Estrada K, Pols HA, Williams FM, McArdle WL, van Meurs JB, Loos RJ, Dermitzakis ET, Ahmadi KR, Hart DJ, Ouwehand WH, Wareham NJ, Barroso I, Sandhu MS, Strachan DP, Livshits G, Spector TD, Uitterlinden AG, Deloukas P (2009). “Meta-analysis of genome-wide scans for human adult stature identifies novel Loci and associations with measures of skeletal frame size”. PLoS Genet. 5 (4): e1000445. doi:10.1371/journal.pgen.1000445. PMCÂ 2661236. PMIDÂ 19343178.
- Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR (2010). “Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score”. Mol. Med. 16 (7–8): 247–53. doi:10.2119/molmed.2009.00159. PMC 2896464. PMID 20379614.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.