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Left posterior fascicular block

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Cafer Zorkun, M.D., Ph.D. [2]

Synonyms and keywords: LPFB; left posterior hemiblock; LPH

Overview

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Left posterior fascicular block is characterized by a mean frontal plane axis of >90° in the absence of other causes of right axis deviation. Left posterior hemiblock (left posterior fascicular block) is infrequent.[1] Its seen either in the setting of either RCA or LAD related pathologies.

Diagnosis

Electrocardiogram

The electrocardiogram findings in left posterior fascicular block include right axis deviation of the QRS complex, wide QRS complexes and a S1Q3 pattern.

References

  1. ABC of Clinical Electrocardiography, Morris F, Edhouse J, Brady WJ, Camm J, 2003

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Historical Perspective

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References

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Pathophysiology

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Pathophysiology

Anatomical Course of the Left Fascicle

The left posterior fascicle is a distal extension of the left main bundle and courses posteriorly toward the posterior papillary muscle which is located in the posterior, medial and inferior aspect of left ventricle and inferoposteriorly toward the left ventricular free wall. [1]

Blood Supply of the Left Posterior Fascicle

The proximal part of the left posterior fascicle is supplied by the artery supplying the atrioventricular (AV) node (often the right coronary artery) and, at times, by septal branches of the left anterior descending (LAD) artery.

References

  1. Pathophysiology of Heart Disease, Lilly LS, 4th edition, 2006

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Causes

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ayokunle Olubaniyi, M.B,B.S [2]

Overview

Isolated left posterior fascicular block is often an uncommon finding[1] owing to the fact that the left posterior fascicle has a dual blood supply, and it is exposed to lower pressures and turbulence, hence, it is rarely damaged. It usually accompanies right bundle branch block (RBBB) or in the setting of arteriosclerotic heart diseases such as myocardial infarction. Other less common causes include: infectious (e.g. diphteritic myocarditis, Chagas disease); genetic (e.g. myotonic dystrophy).

Causes

Life Threatening Causes

Life-threatening causes include conditions which may result in death or permanent disability within 24 hours if left untreated.

Common Causes

Causes by Organ System

Cardiovascular Cardiomyopathy, coronary artery disease, diphteritic myocarditis, hypertensive heart disease, myocardial infarction
Chemical/Poisoning No underlying causes
Dental No underlying causes
Dermatologic No underlying causes
Drug Side Effect No underlying causes
Ear Nose Throat No underlying causes
Endocrine No underlying causes
Environmental No underlying causes
Gastroenterologic No underlying causes
Genetic Kearns-Sayre syndrome, limb-girdle muscular dystrophy, myotonic dystrophy
Hematologic No underlying causes
Iatrogenic No underlying causes
Infectious Disease Chagas disease, diphteritic myocarditis
Musculoskeletal/Orthopedic Limb-girdle muscular dystrophy, myotonic dystrophy
Neurologic Kearns-Sayre syndrome
Nutritional/Metabolic No underlying causes
Obstetric/Gynecologic No underlying causes
Oncologic No underlying causes
Ophthalmologic No underlying causes
Overdose/Toxicity No underlying causes
Psychiatric No underlying causes
Pulmonary Cor pulmonale
Renal/Electrolyte Hyperkalemia
Rheumatology/Immunology/Allergy No underlying causes
Sexual No underlying causes
Trauma No underlying causes
Urologic No underlying causes
Miscellaneous No underlying causes

Causes in Alphabetical Order

References

  1. Godat, FJ.; Gertsch, M. (1993). “Isolated left posterior fascicular block: a reliable marker for inferior myocardial infarction and associated severe coronary artery disease”. Clin Cardiol. 16 (3): 220–6. PMID 8443995. Unknown parameter |month= ignored (help)


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Differentiating Left posterior fascicular block from other Diseases

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References

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Epidemiology and Demographics

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Risk Factors

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References

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Natural History, Complications and Prognosis

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References

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Diagnosis

Diagnosis

History and Symptoms | Physical Examination | Laboratory Findings | Chest X Ray | Electrocardiogram | Echocardiography | Other Imaging Findings | Other Diagnostic Studies

Treatment

Treatment

Medical Therapy | Surgery | Primary Prevention | Secondary Prevention | Cost Effectiveness of Therapy | Future or Investigational Therapies

Case Studies

Case Studies

Case #1


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