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Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.

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Langerhans cell histiocytosis history and symptoms

Introduction

Overview

Overview

Common symptoms of Langerhans cell histiocytosis include bone pain, rash, fever, and failure to thrive.[1][2][3]

History

History

  • When evaluating a patient for Langerhans cell histiocytosis, you should take a detailed history of the presenting symptom (duration, onset, progression), other associated symptoms, and a thorough medication review. Other specific areas of focus when obtaining the history are outlined below:[3]
    • Review family history for members with positive history of the disease
    • Growth velocity chart
    • Any history of excessive thirst and urination
Symptoms

Symptoms

  • Common symptoms of Langerhans cell histiocytosis among children include:[1][2][3]
  • Common symptoms of Langerhans cell histiocytosis among adults include: [4][5][6][7]
References

References

  1. ↑ 1.0 1.1 Langerhans cell histiocytosis. Wikipedia (2015) https://en.wikipedia.org/wiki/Langerhans_cell_histiocytosis Accessed on February, 2 2016
  2. ↑ 2.0 2.1 Langerhans cell histiocytosis. Radiopeadia (2015) http://radiopaedia.org/articles/langerhans-cell-histiocytosis Accessed on February, 3 2016
  3. ↑ 3.0 3.1 3.2 Langerhans Cell Histiocytosis Treatment (PDQ®): Health Professional Version. National Cancer Institute (2015) http://www.cancer.gov/types/langerhans/hp/langerhans-treatment-pdq Accessed on February, 3 2016
  4. ↑ Elena Gkrouzman, Rene H. Cuadra & Jason Jacob (2015). “Langerhans Cell Histiocytosis of the Bone Presenting as Back Pain: An Unusual Diagnosis for a Common Complaint”. Connecticut medicine. 79 (7): 409–414. PMID 26411178. Unknown parameter |month= ignored (help)
  5. ↑ Hiroyuki Tsuchie, Kyoji Okada, Hiroyuki Nagasawa, Michihiro Yano, Hiroshi Nanjyo & Yoichi Shimada (2009). “Langerhans cell histiocytosis of the sternum”. Upsala journal of medical sciences. 114 (2): 121–125. doi:10.1080/03009730802642360. PMID 19396700.
  6. ↑ Koray Aydogdu, Ersin Gunay, Gokturk Findik, Sibel Gunay, Yetkin Agackiran, Sadi Kaya, Nurettin Karaoglanoglu & Irfan Tastepe (2013). “Pulmonary Langerhans cell histiocytosis; characteristics of 11 cases”. Tuberkuloz ve toraks. 61 (4): 333–341. PMID 24506750.
  7. ↑ A. Artigues Barcelo, P. Guiscafre Fontirroig, P. de Miguel Sebastian, R. M. Salgado & M. T. Albiol Varella (2005). “[Fever and hyperprolactinaemia as the onset of Langerhans cell histiocytosis]”. Anales de medicina interna (Madrid, Spain : 1984). 22 (11): 535–537. PMID 16454588. Unknown parameter |month= ignored (help)


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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [2]