Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Laron syndrome historical perspective
Introduction
Overview
Overview
Historical perspective
Historical perspective
It is named after Zvi Laron, the Israeli researcher who, with A. Pertzelan and S. Mannheimer, first reported the condition in 1966[1][2], based upon observations which began in 1958.[3]
Resistance to GH was first reported by Laron in 1966. Since then, severe resistance to GH, characterized by grossly impaired growth despite normal levels of GH in serum, has been termed Laron syndrome.
Homo floresiensis
Recent publications have proposed that Homo floresiensis represented a population with widespread Laron syndrome.[4][5]
References
References
- ↑ Template:WhoNamedIt
- ↑ Laron Z, Pertzelan A, Mannheimer S (1966). “Genetic pituitary dwarfism with high serum concentation of growth hormone–a new inborn error of metabolism?”. Isr. J. Med. Sci. 2 (2): 152–5. PMID 5916640.
- ↑ Laron Z (2004). “Laron syndrome (primary growth hormone resistance or insensitivity): the personal experience 1958-2003”. J. Clin. Endocrinol. Metab. 89 (3): 1031–44. PMID 15001582.
- ↑ Hershkovitz I, Kornreich L, Laron Z (2007). “Comparative skeletal features between Homo floresiensis and patients with primary growth hormone insensitivity (Laron syndrome)”. Am. J. Phys. Anthropol. 134 (2): 198–208. doi:10.1002/ajpa.20655. PMID 17596857.
- ↑ Culotta E (2007). “Paleoanthropology. The fellowship of the hobbit”. Science. 317 (5839): 740–2. doi:10.1126/science.317.5839.740. PMID 17690271.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]