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Leopard syndrome natural history, complications and prognosis

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamed Moubarak, M.D. [2]

Overview

Overview

In general, males are more affected than females. LEOPARD syndrome is not a life threatening diagnosis, cardiomyopathy and other pathologic findings involving the cardiovascular system may be a cause of death in those whose cardiac deformities are profound.

Natural History, Complications and Prognosis

Natural History, Complications and Prognosis

Males are more likely than females to be affected with LEOPARD syndrome.[1] LEOPARD syndrome is not a life threatening diagnosis, but Obstructive cardiomyopathy and other pathologic findings involving the cardiovascular system may be a cause of death in those whose cardiac deformities are profound. It is suggested that, once diagnosed, individuals be routinely followed by a cardiologist, endocrinologist, dermatologist, and other appropriate specialties as symptoms present.

References

References

  1. Voron DA, Hatfield HH, Kalkhoff RK (1976). “Multiple lentigines syndrome. Case report and review of the literature”. Am J Med. 60 (3): 447–56. PMID 1258892.

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