Adof Weil is the first physician described about the severe form of leptospirosis and the name Weil’s disease is named after him in the year 1886. He also described the jaundice with splenomegaly, renal failure, skin rash and conjunctival suffusion.^[1] Japanees scientists Kitamura and Hara named this disease as autumn fever and seven day disease in 1918.^[2]

• The association between the disease prevalence and occupational status for leptospirosis is first described by Alston and Broom in 1958. They also found that it more prevalent in farmers who are working in cane farm and named the disease as cane cutter’s disease, swine-herd’s disease, Schlammfieber disease or mud fever.^[3]
• Leptospires are first demonstrated in the year 1907 by Stimson and he coined the name as Spirocheta interrogans.^[2]
• In 1915 German researchers Hubener, Uhlenhuth Fromme first time succeeded in transmitting the infection to guinea-pigs and demonstrating the leptospires in guinea-pig tissues and they named the organisms as Spirochaeta nodosa and Spirochaeta icterogenes.^[4]
• Japanese research group Ido et al. described the mechanism of transmission from rats to humans in 1917 and research groups Noguchi and Stokes et al. from Europe and United States respectively confirmed the same in 1917.^[5]
• Genus name Leptospira was coined to separate other spirochetes from Treponema pallidum by Noguchi in 1918.^[6]