Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Levofloxacin overdose
Introduction
Overdose Information
General overdose information
Treatment
General overdose information
Levofloxacin exhibits a low potential for acute toxicity. Mice, rats, dogs and monkeys exhibited
the following clinical signs after receiving a single high dose of levofloxacin: ataxia, ptosis,
decreased locomotor activity, dyspnea, prostration, tremors, and convulsions. Doses in excess of
1500 mg/kg orally and 250 mg/kg i.v. produced significant mortality in rodents. Return to top
Treatment
In the event of an acute overdosage, the stomach should be emptied. The patient should be observed and appropriate hydration maintained. Levofloxacin is not efficiently removed by hemodialysis or
peritoneal dialysis. Return to top
Adapted from the FDA Package Insert.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]