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Levuglandin

Introduction

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Levuglandins are reactive aldehydes formed by the spontaneous rearrangement of prostaglandin H (PGH). They are nonclassic eicosanoids. One species, levuglandin E2, (LGE2), forms neurotoxic adducts with amyloid beta.[1]

References

  1. ↑ Bautaud; et al. “PGH -derived levuglandin adducts increase the neurotoxicity of Amyloid Î’1–42“ (pdf). Biochemistry. 38: 9389–9396. Retrieved 2007-10-02.