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Lim homeobox 9
Introduction
LIM homeobox 9 is a protein that in humans is encoded by the LHX9 gene.[1]
Function
Function
This gene encodes a member of the LIM homeobox gene family of developmentally expressed transcription factors. The encoded protein contains a homeodomain and two cysteine-rich zinc-binding LIM domains involved in protein-protein interactions. The protein is highly similar to a mouse protein that causes gonadal agenesis when inactivated, suggesting a role in gonadal development. Alternative splicing results in multiple transcript variants.
Further reading
Further reading
- Avraham O, Hadas Y, Vald L, Zisman S, Schejter A, Visel A, Klar A (2009). “Transcriptional control of axonal guidance and sorting in dorsal interneurons by the Lim-HD proteins Lhx9 and Lhx1”. Neural Dev. 4: 21. doi:10.1186/1749-8104-4-21. PMCÂ 2704203. PMIDÂ 19545367.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.