Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Lipoprotein-associated phospholipase A2 (Lp-PLA2)
Introduction
Overview
Lipoprotein-associated phospholipase A2 (Lp-PLA2) is an enzyme that can modify low-density lipoproteins and may be involved in atherogenesis and the risk of coronary artery disease. In a nested case-control study, patients in the highest quintile of Lp-PLA2 levels had nearly twice the odds of coronary events compared with patients in the lowest quintile.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]