
Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Liposarcoma medical therapy
Introduction
Overview
Overview
Medical therapy for liposarcoma includes Chemotherapy, chemoradiation, immunotherapy, and targeted therapy.
Medical Therapy
Medical Therapy
Chemotherapy
- Chemotherapy may be used with radiation therapy either before or after surgery to shrink the tumor or kill any remaining cancer cells.
- If the cancer has spread to other areas of the body, chemotherapy may be used to shrink tumors and reduce the associated pain and discomfort.
- Patients with soft tissue sarcomas usually receive chemotherapy intravenously.
Chemoradiation
- Sometimes the targeted therapy is given along with radiation.
- They may be given together or at different intervals.
Targeted Therapy
- It stops the growth of the molecules involved in growth of cancer cells.
- It blocks the growth signals.
- Most targeted therapy comes in pill form and some needs to be injected.
Immunotherapy
- Immunotherapy increases the activity of the immune system and improves body’s ability to find and destroy cancer cells.
- Few of the drugs used for immune therapy are listed below.[1]
| Drug | Type of drug |
|---|---|
| Bevacizumab | Targeted therapy |
| Celecoxib | Targeted therapy |
| Crizotinib | Targeted therapy |
| Dacarbazine | Chemotherapy |
| Dasatinib | Targeted therapy |
| Docetaxel | Chemotherapy |
| Doxorubicin | Chemotherapy |
| Epirubicin hydrochloride | Chemotherapy |
| Everolimus | Chemotherapy |
| Gemcitabine hydrochloride | Chemotherapy |
| Ifosfamide | Chemotherapy |
| Imatinib mesylate | Targeted therapy |
| Interferon alpha 2B | Immunotherapy |
| Mesna | Chemotherapy |
| Methotrexate | Chemotherapy |
| Nilotinib | Chemotherapy |
| Paclitaxel | Chemotherapy |
| Pazopanib | Targeted therapy |
| Regorafenib | Targeted therapy |
| Sorafenib tosylate | Targeted therapy |
| Sirolimus | Chemotherapy |
| Sulindac | Chemotherapy |
| Sunitinib malate | Targeted therapy |
| Tamoxifen citrate | Targeted therapy |
| Temozolomide | Chemotherapy |
| Toremifene citrate | Targeted therapy |
| Vinblastine citrate | Chemotherapy |
| Vinblastine tartrate | Chemotherapy |
Regimen
| Drugs | Dose |
|---|---|
| Doxorubicin | Doxorubicin 75 mg/m2; 28 day cycle |
| Pegylated liposomal doxorubicin | 40 – 50 mg/m2Â ; 28 day cycle |
| AI regimen | Doxorubicin 25 mg/m2, Ifosfamide 3 g/m2 21 day cycle |
| MAID regimen | Doxorubicin 20 mg/m2, Ifosfamide 2.5 g/m2, Dacarbazine 300mg/m2 21 day cycle |
| AD regimen | Doxorubicin 20 mg/m2, Dacarbazine 300 mg/m2; 21 day cycle |
| Metronomic cyclophosphamide | Oral daily cyclophosphamide 50mg/day for 21 days on 28 day cycle |
| Docetaxel–Gemcitabine | Gemcitabine 900 mg/m2 , Docetaxel 100 mg/m2 for 21 day cycle |
| Trabectedin | Trabectedin 1.5 mg/m2 21 day cycle[2] |
References
References
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Â ; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]
