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Health Dictionary

Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.

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Loefflers syndrome chest x ray

Introduction

Overview

Overview

A chest x-ray may be helpful in the diagnosis of Löffler syndrome. Findings on an x-ray suggestive of Löffler syndrome include migratory densities. Chest x-ray usually shows abnormal shadows that can be unilateral or bilateral. Generally, densities are peripheral and present with both interstitial and alveolar pattern (at the same time), they are a few centimeters in diameter, and are transient, migratory, and disappear completely within 2-4 weeks. Pleural effusions is not common in Loeffler syndrome, but there are reports of pleural effusion in patients with drug-induced pulmonary eosinophilia. (nitrofurantoin, valproic acid)

X Ray

X Ray

An x-ray may be helpful in the diagnosis of Löffler syndrome. Findings on an x-ray suggestive of Löffler syndrome include:[1][2][1][3] [4][5][6][7][8]

  • Chest x-ray usually shows abnormal shadows that can be unilateral or bilateral.
  • Generally peripheral densities
  • Present with both interstitial and alveolar pattern (at the same time).
  • Usually a few centimeters in diameter, but larger areas of consolidation are possible
  • Generally transient, migratory, and disappear completely within 2-4 weeks.
  • Pleural effusions is not common in Loeffler syndrome, but there are reports of pleural effusion in patients with drug-induced pulmonary eosinophilia. (nitrofurantoin, valproic acid)
Acute eosinophilic pneumonia. Case courtesy of Dr Yair Glick, <a href=”https://radiopaedia.org/“>Radiopaedia.org</a>. From the case <a href=”https://radiopaedia.org/cases/53840“>rID: 53840</a>
Allergic bronchopulmonary aspergillosis (ABPA). Case courtesy of A.Prof Frank Gaillard, <a href=”https://radiopaedia.org/“>Radiopaedia.org</a>. From the case <a href=”https://radiopaedia.org/cases/15388“>rID: 15388</a>
Follow-up

Follow-up

  • 4-6 weeks after initial presentation: Repeat chest radiography (document resolution of pulmonary infiltrates)
References

References

  1. ↑ 1.0 1.1 Te Booij M, de Jong E, Bovenschen HJ (2010) Löffler syndrome caused by extensive cutaneous larva migrans: a case report and review of the literature. Dermatol Online J 16 (10):2. PMID: 21062596
  2. ↑ Chitkara RK, Krishna G (2006) Parasitic pulmonary eosinophilia. Semin Respir Crit Care Med 27 (2):171-84. DOI:10.1055/s-2006-939520 PMID: 16612768
  3. ↑ Ekin S, Sertogullarindan B, Gunbatar H, Arisoy A, Yildiz H (2016) Loeffler’s syndrome: an interesting case report. Clin Respir J 10 (1):112-4. DOI:10.1111/crj.12173 PMID: 24931460
  4. ↑ Caulet T (1957) [Loffler syndrome and pulmonary eosinophilia.] Gaz Med Fr 64 (20):1737-8 passim. PMID: 13480465
  5. ↑ (1968) Löffler’s syndrome. Br Med J 3 (5618):569-70. PMID: 5667987
  6. ↑ SASLAW MS, BOWMAN JA (1946) Loeffler’s syndrome. J Fla Med Assoc 32 ():373. PMID: 21007279
  7. ↑ SPECTOR HI (1945) Loeffler’s syndrome (transient pulmonary infiltrations with eosinophilia); report of a case and a review of the available literature. Dis Chest 11 ():380-91. PMID: 21025484
  8. ↑ GREIG ED (1945) On tropical eosinophilia associated with pulmonary signs (Loeffler’s syndrome). J Trop Med Hyg 48 ():149-51. PMID: 21010826

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Soroush Seifirad, M.D.[2]