Lymphomatoid granulomatosis classification

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Kamal Akbar, M.D.[2]

Overview

Lymphomatoid granulomatosis may be classified according to a grading system into low grade and high grade.

Classification

Lymphomatoid granulomatosis may be classified according to a grading system which denotes the amount of EBV positive large B-cell malignant cells that are present. Deciphering the severity of the disease is crucial in determining which treatment options to pursue. The condition is classified into two subtypes:^[1]

Low grade:
- Small amount of large atypical cells
- Few mitotic figures
- Minute amount of necrosis
- Some cases resolve on there own

High grade:
- Preponderant population of large atypical cells
- Profuse necrosis

References

↑ Roschewski M, Wilson WH (2012). “Lymphomatoid granulomatosis”. Cancer J. 18 (5): 469–74. doi:10.1097/PPO.0b013e31826c5e19. PMID 23006954.

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[pmid23006954-1] Roschewski M, Wilson WH (2012). “Lymphomatoid granulomatosis”. Cancer J. 18 (5): 469–74. doi:10.1097/PPO.0b013e31826c5e19. PMID 23006954.

[1]

Lymphomatoid granulomatosis classification

Overview

Classification

References

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