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Lymphoplasmacytic lymphoma MRI

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sara Mohsin, M.D.[2]

Overview

Overview

There are no specific MRI findings associated with lymphoplasmacytic lymphoma. However, MRI of the brain, spinal cord and orbits is especially important while assessing hyperviscosity and for diagnosing Bing-Neel syndrome.

MRI

MRI

MRI brain coronal view shows diffuse meningeal enhancement in a patient with Bing-Neel syndrome. [https://openi.nlm.nih.gov/detailedresult.php?img=PMC4837273_CRIHEM2016-3931709.002&query=waldenstrom+macroglobulinaemia&it=xg&req=4&npos=69 Source: Halperin D. et al, Whipps Cross Hospital, London E11 1NR, UK.
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Coronal T1-weighted (TR 600, TE 30) 3mm noncontrast sections through the inner ear in a patient with Waldenstrom macroglobulinemia with bilateral hearing loss. Arrows indicate hemorrhage within the labyrinth. [https://openi.nlm.nih.gov/detailedresult.php?img=PMC4891550_gr2&query=waldenstrom+macroglobulinaemia&it=xg&req=4&npos=67 Source: Shibata DK. et al.
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Axial T1-weighted (TR 700, TE 30) 3mm noncontrast sections through the petrous bone in a patient with Waldenstrom macroglobulinemia with bilateral hearing loss. Arrows indicate T1 shortening within the labyrinth. [https://openi.nlm.nih.gov/detailedresult.php?img=PMC4891550_gr1&query=waldenstrom+macroglobulinaemia&it=xg&req=4&npos=66 Source: Shibata DK. et al.
]
References

References

  1. ↑ O’Neil DS, Francescone MA, Khan K, Bachir A, O’Connor OA, Sawas A (2018). “A Case of Bing-Neel Syndrome Successfully Treated with Ibrutinib”. Case Rep Hematol. 2018: 8573105. doi:10.1155/2018/8573105. PMC 6136466. PMID 30228918.
  2. ↑ Minnema MC, Kimby E, D’Sa S, Fornecker LM, Poulain S, Snijders TJ; et al. (2017). “Guideline for the diagnosis, treatment and response criteria for Bing-Neel syndrome”. Haematologica. 102 (1): 43–51. doi:10.3324/haematol.2016.147728. PMC 5210231. PMID 27758817.
  3. ↑ Tallant A, Selig D, Wanko SO, Roswarski J (2018). “First-line ibrutinib for Bing-Neel syndrome”. BMJ Case Rep. 2018. doi:10.1136/bcr-2018-226102. PMID 30279255.

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