Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
MAOA
Introduction
Monoamine oxidase A, also known as MAOA, is a human gene.
This gene encodes monoamine oxidase A, an enzyme that degrades amine neurotransmitters, such as dopamine, norepinephrine, and serotonin. The protein localizes to the mitochondrial outer membrane. The gene is adjacent to a related gene on the opposite strand of chromosome X. Mutation in this gene results in monoamine oxidase deficiency, or Brunner syndrome.[1]
Further reading
Further reading
- Edmondson DE, Binda C, Mattevi A (2004). “The FAD binding sites of human monoamine oxidases A and B.”. Neurotoxicology. 25 (1–2): 63–72. doi:10.1016/S0161-813X(03)00114-1. PMID 14697881.
- Craig IW (2007). “The importance of stress and genetic variation in human aggression”. Bioessays. 29 (3): 227–36. doi:10.1002/bies.20538. PMID 17295220.