Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
MEMO1
Introduction
Mediator of cell motility 1 is a protein that in humans is encoded by the MEMO1 gene.[1]
Further reading
Further reading
- Meira M, Masson R, Stagljar I, Lienhard S, Maurer F, Boulay A, Hynes NE (March 2009). “Memo is a cofilin-interacting protein that influences PLCgamma1 and cofilin activities, and is essential for maintaining directionality during ErbB2-induced tumor-cell migration”. Journal of Cell Science. 122 (Pt 6): 787–97. doi:10.1242/jcs.032094. PMID 19223396.
- Marone R, Hess D, Dankort D, Muller WJ, Hynes NE, Badache A (June 2004). “Memo mediates ErbB2-driven cell motility”. Nature Cell Biology. 6 (6): 515–22. doi:10.1038/ncb1134. PMID 15156151.
- Reymond A, Friedli M, Henrichsen CN, Chapot F, Deutsch S, Ucla C, Rossier C, Lyle R, Guipponi M, Antonarakis SE (November 2001). “From PREDs and open reading frames to cDNA isolation: revisiting the human chromosome 21 transcription map”. Genomics. 78 (1–2): 46–54. doi:10.1006/geno.2001.6640. PMID 11707072.
- Qiu C, Lienhard S, Hynes NE, Badache A, Leahy DJ (February 2008). “Memo is homologous to nonheme iron dioxygenases and binds an ErbB2-derived phosphopeptide in its vestigial active site”. The Journal of Biological Chemistry. 283 (5): 2734–40. doi:10.1074/jbc.M703523200. PMID 18045866.
- Hu YH, Warnatz HJ, Vanhecke D, Wagner F, Fiebitz A, Thamm S, Kahlem P, Lehrach H, Yaspo ML, Janitz M (June 2006). “Cell array-based intracellular localization screening reveals novel functional features of human chromosome 21 proteins”. BMC Genomics. 7: 155. doi:10.1186/1471-2164-7-155. PMC 1526728. PMID 16780588.
- Zaoui K, Honoré S, Isnardon D, Braguer D, Badache A (November 2008). “Memo-RhoA-mDia1 signaling controls microtubules, the actin network, and adhesion site formation in migrating cells”. The Journal of Cell Biology. 183 (3): 401–8. doi:10.1083/jcb.200805107. PMC 2575782. PMID 18955552.