Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Macrocytic anemia risk factors
Introduction
Overview
Overview
Common risk factors of megaloblastic anemia include nutritional factors, alcoholism, elderly, pregnant, vegans, and malabsorptive syndromes.
Risk Factors
Risk Factors
Common risk factors of megaloblastic anemia:[1][2][3][4]
- Folate deficiency
- Nutritional deficiency
- Strict vegan diet
- Malabsorptive disorders such as blind loops/bacterial overgrowth, sprue, Whipple’s and crohn’s
- Diphillobothrium latum infection (a competitor for B12 absorption)
- Elderly age
- Alcohol use
- Narcotic abuse
- Physiologic or pathologic states of increased metabolic demand
- Pregnancy
- Infancy
- Low grade hemolysis
- Malignancy
- Chronic hemodialysis
- Autoimmune disease
- Hashimoto’s
- Vitiligo
- Diabetes
- Adrenal insufficiency (Schmitt’s Syndrome)
References
References
- ↑ Carmel R (May 1996). “Prevalence of undiagnosed pernicious anemia in the elderly”. Arch. Intern. Med. 156 (10): 1097–100. PMID 8638997.
- ↑ Toh BH, van Driel IR, Gleeson PA (November 1997). “Pernicious anemia”. N. Engl. J. Med. 337 (20): 1441–8. doi:10.1056/NEJM199711133372007. PMID 9358143.
- ↑ Rusak E, Chobot A, Krzywicka A, Wenzlau J (September 2016). “Anti-parietal cell antibodies – diagnostic significance”. Adv Med Sci. 61 (2): 175–179. doi:10.1016/j.advms.2015.12.004. PMID 26918709.
- ↑ Bizzaro N, Antico A (2014). “Diagnosis and classification of pernicious anemia”. Autoimmun Rev. 13 (4–5): 565–8. doi:10.1016/j.autrev.2014.01.042. PMID 24424200.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Shyam Patel [2] Associate Editor(s)-in-Chief: Amandeep Singh M.D.[3]