The macule is the simplest dermatological lesion. It is flat and can only be seen and not felt. The macule is noted by a change in color of the skin. It may be brown, blue, red or exhibit a lesser pigment or an absence of pigment. The color of the lesion is one way in which a diagnosis may be focused.

Macules may develop as a result of cystic or otherwise severe acne. They occur after a pimple or cyst has healed, and may remain for up to six months. They are sometimes known in such cases as “pseudo-scars”, but unlike true scars they are not permanent.