Malignant peripheral nerve sheath tumor history and symptoms

Patients present with a rapidly enlarging mass that may be painful or cause local neurological symptoms such as weakness or paresthesias. The development of new, worsening, or persistent pain in the neurofibroma of a patient with NF1 is an important symptom that should always be conscientiously evaluated, even if there was already pre-existing chronic discomfort from the lesion.The most common sites of involvement include the nerve roots and bundles in the extremities and pelvis, particularly the sciatic nerve. Symptoms of malignant peripheral nerve sheath tumor include peripheral edema, difficulty in moving the affected extremity, pain, and numbness.^[1]

Symptoms of malignant peripheral nerve sheath tumor include:^[1]

• Peripheral edema
• Difficulty in moving the affected extremity
• Pain
• Numbness
• Burning

Template:WH Template:WS