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Mast cell leukemia natural history, complications, and prognosis

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sogand Goudarzi, MD [2]

Overview

Overview

If left untreated, patients with mast cell leukemia may progress to develop weight loss, ascites, and bone abnormalities.Common complications of mast cell leukemia include hepatosplenomegaly, lymphadenopathy, and osteoporosis.[1] Prognosis is generally poor, and the median survival time is less than six months.[2]

Natural History, Complications, and Prognosis

Natural History, Complications, and Prognosis

If left untreated, patients with mast cell leukemia may progress to develop weight loss, ascites, and bone abnormalities.Common complications of mast cell leukemia include hepatosplenomegaly, lymphadenopathy, and osteoporosis.[1] Prognosis is generally poor, and the median survival time is less than six months.[2]

References

References

  1. 1.0 1.1 Joris, Magalie; Georgin-Lavialle, Sophie; Chandesris, Marie-Olivia; Lhermitte, Ludovic; Claisse, Jean-François; Canioni, Danielle; Hanssens, Katia; Damaj, Gandhi; Hermine, Olivier; Hamidou, Mohammed (2012). “Mast Cell Leukaemia: c-KIT Mutations Are Not Always Positive”. Case Reports in Hematology. 2012: 1–6. doi:10.1155/2012/517546. ISSN 2090-6560.
  2. 2.0 2.1 Georgin-Lavialle, S.; Lhermitte, L.; Dubreuil, P.; Chandesris, M.-O.; Hermine, O.; Damaj, G. (2012). “Mast cell leukemia”. Blood. 121 (8): 1285–1295. doi:10.1182/blood-2012-07-442400. ISSN 0006-4971.

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