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Mast cell leukemia natural history, complications, and prognosis

Introduction

Overview

Overview

If left untreated, patients with mast cell leukemia may progress to develop weight loss, ascites, and bone abnormalities.Common complications of mast cell leukemia include hepatosplenomegaly, lymphadenopathy, and osteoporosis.[1] Prognosis is generally poor, and the median survival time is less than six months.[2]

Natural History, Complications, and Prognosis

Natural History, Complications, and Prognosis

If left untreated, patients with mast cell leukemia may progress to develop weight loss, ascites, and bone abnormalities.Common complications of mast cell leukemia include hepatosplenomegaly, lymphadenopathy, and osteoporosis.[1] Prognosis is generally poor, and the median survival time is less than six months.[2]

References

References

  1. ↑ 1.0 1.1 Joris, Magalie; Georgin-Lavialle, Sophie; Chandesris, Marie-Olivia; Lhermitte, Ludovic; Claisse, Jean-FranΓ§ois; Canioni, Danielle; Hanssens, Katia; Damaj, Gandhi; Hermine, Olivier; Hamidou, Mohammed (2012). “Mast Cell Leukaemia: c-KIT Mutations Are Not Always Positive”. Case Reports in Hematology. 2012: 1–6. doi:10.1155/2012/517546. ISSNΒ 2090-6560.
  2. ↑ 2.0 2.1 Georgin-Lavialle, S.; Lhermitte, L.; Dubreuil, P.; Chandesris, M.-O.; Hermine, O.; Damaj, G. (2012). “Mast cell leukemia”. Blood. 121 (8): 1285–1295. doi:10.1182/blood-2012-07-442400. ISSNΒ 0006-4971.

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sogand Goudarzi, MD [2]