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May Hegglin anomaly

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]


May Hegglin’s anomaly, as it is also known, is a rare genetic disorder of the blood platelets that causes them to be abnormally large. Also, this anomaly causes abnormalities in the white blood cells known as leukocytes.

Presentation

Presentation

In the leukocytes, the presence of very small rods (around 3 micrometers), or Dohle bodies can be seen in the cytoplasm.

Treatment

Treatment

In many cases, May Hegglin’s requires no treatment. However, in extreme cases, blood platelet transfusions may be necessary

Causes

Causes

An association with MYH9 has been described.[1]

References

References

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