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Health Dictionary

Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.

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Mediastinitis natural history, complications and prognosis

Introduction

Overview

Overview

If left untreated, fibrosing mediastinitis may progress to sepsis and subsequently, death.[1] Mortality rates related to mediastinitis vary, though some estimates predict rates greater than 60%.[2] Common complications of mediastinitis include sepsis and pneumonia.

Natural History

Natural History

If left untreated, fibrosing mediastinitis may progress to sepsis and subsequently, death.[1] Mortality rates related to mediastinitis vary, with some estimates predicting rates greater than 60%.[2]

Complications

Complications

Common complications of mediastinitis include the following:[1][3]

Prognosis

Prognosis

Generally, patients with mediastinitis have a poor prognosis with a mortality rate near 40%.[4] Mediastinitis among post-sternotomy patients has a particularly poor prognosis with an elevated risk of mortality near 60%.[2] Prognosis improves with antimicrobial therapy.[1]

References

References

  1. ↑ 1.0 1.1 1.2 1.3 Mediastinitis: a potentially lethal infection. Thoracics (2012). http://thoracics.org/2012/03/03/mediastinitis-noncardiac-surgery/ Accessed on September 25, 2015.
  2. ↑ 2.0 2.1 2.2 Martínez Vallina P, Espinosa Jiménez D, Hernández Pérez L, Triviño Ramírez A (2011). “[Mediastinitis]”. Arch Bronconeumol. 47 Suppl 8: 32–6. doi:10.1016/S0300-2896(11)70065-5. PMID 23351519.
  3. ↑ Fibrosing Mediastinitis. National Organization for Rare Disorders (2015). https://rarediseases.org/rare-diseases/fibrosing-mediastinitis/ Accessed on September 25, 2015
  4. ↑ Macrí P, Jiménez MF, Novoa N, Varela G (2003). “[A descriptive analysis of a series of patients diagnosed with acute mediastinitis]”. Arch. Bronconeumol. (in Spanish; Castilian). 39 (9): 428–30. PMID 12975075.

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Anthony Gallo, B.S. [2]