Medullary thyroid cancer epidemiology and demographics

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]

Overview

The incidence of medullary thyroid cancer is approximately 14.3 per 100,000 individuals worldwide. The incidence of medullary thyroid cancer increases with age; Sporadic form of medullary thyroid cancer commonly presents in the fifth and sixth decade of life. The familial form tends to appear earlier in life.

Epidemiology and Demographics

Incidence

The overall incidence of thyroid cancer is approximately 14.3 per 100,000 individuals worldwide.^[1]^[2]

Age

The incidence of medullary thyroid cancer increases with age.^[3]
Sporadic form of medullary thyroid cancer commonly presents in the fifth and sixth decade of life.^[4]
The familial form tends to appear earlier in life.

Gender

Medullary thyroid cancer affects women more frequently than men. However, this gender disparity tends to decrease by advancing the age of individuals.^[3]

Race

Medullaty thyroid cancer is more common among white and hispanic ethnicities than Asian/Pacific Islanders and blacks.^[3]^[5]

Case fatality/Mortality rate

The overall mortality rate of thyroid cancer is 0.5 per 100,000 worldwide.^[2]

References

↑ Davies, Louise; Welch, H. Gilbert (2006). “Increasing Incidence of Thyroid Cancer in the United States, 1973-2002”. JAMA. 295 (18): 2164. doi:10.1001/jama.295.18.2164. ISSN 0098-7484.
↑ ^2.0 ^2.1 Davies, Louise; Welch, H. Gilbert (2014). “Current Thyroid Cancer Trends in the United States”. JAMA Otolaryngology–Head & Neck Surgery. 140 (4): 317. doi:10.1001/jamaoto.2014.1. ISSN 2168-6181.
↑ ^3.0 ^3.1 ^3.2 Aschebrook-Kilfoy, Briseis; Ward, Mary H.; Sabra, Mona M.; Devesa, Susan S. (2011). “Thyroid Cancer Incidence Patterns in the United States by Histologic Type, 1992–2006”. Thyroid. 21 (2): 125–134. doi:10.1089/thy.2010.0021. ISSN 1050-7256.
↑ Wells, Samuel A.; Asa, Sylvia L.; Dralle, Henning; Elisei, Rossella; Evans, Douglas B.; Gagel, Robert F.; Lee, Nancy; Machens, Andreas; Moley, Jeffrey F.; Pacini, Furio; Raue, Friedhelm; Frank-Raue, Karin; Robinson, Bruce; Rosenthal, M. Sara; Santoro, Massimo; Schlumberger, Martin; Shah, Manisha; Waguespack, Steven G. (2015). “Revised American Thyroid Association Guidelines for the Management of Medullary Thyroid Carcinoma”. Thyroid. 25 (6): 567–610. doi:10.1089/thy.2014.0335. ISSN 1050-7256.
↑ Lairmore, Terry C.; Diesen, Diana; Goldfarb, Melanie; Milas, Mira; Ying, Anita K.; Sharma, Jyotirmay; McIver, Bryan; Wong, Richard J.; Randolph, Greg (2015). “AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY DISEASE STATE CLINICAL REVIEW: TIMING OF MULTIPLE ENDOCRINE NEOPLASIA THYROIDECTOMY AND EXTENT OF CENTRAL NECK LYMPHADENECTOMY”. Endocrine Practice. 21 (7): 839–847. doi:10.4158/EP14463.DSCR. ISSN 1530-891X.

Template:WikiDoc Sources

[DaviesWelch2006-1] Davies, Louise; Welch, H. Gilbert (2006). “Increasing Incidence of Thyroid Cancer in the United States, 1973-2002”. JAMA. 295 (18): 2164. doi:10.1001/jama.295.18.2164. ISSN 0098-7484.

[DaviesWelch2014-2] 2.0 ^2.1 Davies, Louise; Welch, H. Gilbert (2014). “Current Thyroid Cancer Trends in the United States”. JAMA Otolaryngology–Head & Neck Surgery. 140 (4): 317. doi:10.1001/jamaoto.2014.1. ISSN 2168-6181.

[Aschebrook-KilfoyWard2011-3] 3.0 ^3.1 ^3.2 Aschebrook-Kilfoy, Briseis; Ward, Mary H.; Sabra, Mona M.; Devesa, Susan S. (2011). “Thyroid Cancer Incidence Patterns in the United States by Histologic Type, 1992–2006”. Thyroid. 21 (2): 125–134. doi:10.1089/thy.2010.0021. ISSN 1050-7256.

[WellsAsa2015-4] Wells, Samuel A.; Asa, Sylvia L.; Dralle, Henning; Elisei, Rossella; Evans, Douglas B.; Gagel, Robert F.; Lee, Nancy; Machens, Andreas; Moley, Jeffrey F.; Pacini, Furio; Raue, Friedhelm; Frank-Raue, Karin; Robinson, Bruce; Rosenthal, M. Sara; Santoro, Massimo; Schlumberger, Martin; Shah, Manisha; Waguespack, Steven G. (2015). “Revised American Thyroid Association Guidelines for the Management of Medullary Thyroid Carcinoma”. Thyroid. 25 (6): 567–610. doi:10.1089/thy.2014.0335. ISSN 1050-7256.

[LairmoreDiesen2015-5] Lairmore, Terry C.; Diesen, Diana; Goldfarb, Melanie; Milas, Mira; Ying, Anita K.; Sharma, Jyotirmay; McIver, Bryan; Wong, Richard J.; Randolph, Greg (2015). “AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY DISEASE STATE CLINICAL REVIEW: TIMING OF MULTIPLE ENDOCRINE NEOPLASIA THYROIDECTOMY AND EXTENT OF CENTRAL NECK LYMPHADENECTOMY”. Endocrine Practice. 21 (7): 839–847. doi:10.4158/EP14463.DSCR. ISSN 1530-891X.

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