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Medullary thyroid cancer laboratory findings

Introduction

Overview

Overview

Laboratory findings consistent with the diagnosis of medullary thyroid cancer include decreased thyroid stimulating hormone, elevated calcitonin, and decreased calcium.

Laboratory Findings

Laboratory Findings

  • Blood or imaging tests may be done prior to or in lieu of a biopsy. The following blood tests are conducted:
  • Tests for serum thyroid autoantibodies are done to rule out autoimmune thyroid disease.
  • Laboratory findings consistent with the diagnosis of multiple endocrine neoplasia type 2 are tabulated below.
Laboratory findings
Test Findings
Metabolic Decreased thyroid stimulating hormone
Antithyroid antibodies
Elevated calcitonin
Decreased calcium
Adapted from Arzu Tatlıpınar1 and İlkay Kartal [Updated 2015].The Evaluation of Thyroid Nodules. Journal of Thyroid Disorders & Therapy.2015.[1]
Laboratory tests Normal Range Abnormal value
Serum
Thyroid stimulating hormone 0.4 – 4.0 milli-international units per liter <0.4 or >4.0
Antithyroid antibodies <35 IU/mL >35 IU/mL
Serum calcitonin less than 10pg/mL >=100 pg/mL
Serum calcium 8.9-10.1 mg/dL > 10.1 mg/dL or < 8.9 mg/dL

References

  1. ↑ İlkay Kartal, Arzu Tatlıpınar (2014). “The Evaluation of Thyroid Nodules”. Journal of Thyroid Disorders and Therapy. 04 (02). doi:10.4172/2167-7948.1000181. ISSN 2167-7948.

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]