Medullary thyroid cancer risk factors

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]

Overview

Common risk factors in the development of medullary thyroid cancer are family history of medullary thyroid cancer and family history of multiple endocrine neoplasia.

Risk Factors

Common risk factors associated with medullary thyroid cancer include:^[1]^[2]
- Family history of medullary thyroid cancer
- Family history of multiple endocrine neoplasia
- A prior history of pheochromocytoma, mucosal neuroma, or hyperparathyroidism

References

↑ Marsh DJ, Andrew SD, Eng C, Learoyd DL, Capes AG, Pojer R, Richardson AL, Houghton C, Mulligan LM, Ponder BA, Robinson BG (March 1996). “Germline and somatic mutations in an oncogene: RET mutations in inherited medullary thyroid carcinoma”. Cancer Res. 56 (6): 1241–3. PMID 8640806.
↑ Thyroid Cancer Cancer.gov (2015). http://www.cancer.gov/types/thyroid/hp/thyroid-treatment-pdq#link/stoc_h2_2- Accessed on October, 29 2015

Overview