Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Melanocytic nevus historical perspective
Introduction
Overview
Overview
Dysplastic nevus was first discovered by Clark and his colleagues in 1978.
Historical Perspective
Historical Perspective
- Dysplastic nevus was first discovered by Clark and his colleagues in 1978.[1]
- The name ‘dysplastic nevus’ was proposed since they are benign melanocytic nevi that include cytologic atypia, similar to dysplastic lesions of other organs, such as the cervix.[2]
- At one time in the 1950s and 60s, (and, to lesser extent, currently) a mole was known as a “beauty mark” when it appeared in certain spots on a woman’s face. Examples include Marilyn Monroe, model Cindy Crawford and singer Madonna. Madonna’s facial mole — below her right nostril — has been surgically removed.
References
References
- ↑ Clark WH, Reimer RR, Greene M, Ainsworth AM, Mastrangelo MJ (1978). “Origin of familial malignant melanomas from heritable melanocytic lesions. ‘The B-K mole syndrome‘“. Arch Dermatol. 114 (5): 732–8. PMID 646394.
- ↑ Elder DE, Goldman LI, Goldman SC, Greene MH, Clark WH (1980). “Dysplastic nevus syndrome: a phenotypic association of sporadic cutaneous melanoma”. Cancer. 46 (8): 1787–94. doi:10.1002/1097-0142(19801015)46:8<1787::aid-cncr2820460816>3.0.co;2-s. PMID 7427881.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: : Qurrat-ul-ain Abid, M.D.[2]; Roukoz A. Karam, M.D.[3]