Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Menopause laboratory findings
Introduction
Overview
Overview
Laboratory findings consistent with the diagnosis of menopause include an elevated Follicle Stimulating Hormone > 40 mIU/mL, decreased estradiol level <20 pg/ml, and decreased serum of the Anti-Mullerian Hormone level < 0.20 ng/ml. In addition to other blood tests that are related to premature menopause such as positive karyotype test of FMR1 in Fragile X syndrome and decrease of Thyroid-stimulating hormone.
laboratory findings
laboratory findings
Laboratory findings consistent with the diagnosis of menopause include:
- An elevated serum of Follicle Stimulating Hormone (FSH) > 40 mIU/mL is diagnostic of menopause, but an elevated FSH level on two blood samples is diagnostic of premature menopause with intervals of about 4–6 weeks between samples.[1]
- A decreased serum of the AMH level < 0.20 ng/ml is normal in postmenopausal women, but decreased serum of the Anti-Mullerian Hormone level is a diagnostic test of premature menopause[2]
- A decreased estradiol level <20 pg/ml.
- Positive of karyotype analysis of FMR1 in Fragile X syndrome case.
- Decrease of Thyroid-stimulating hormone (TSH) in thyroid dysfunction case.[3]
References
References
- ↑ Burger HG (1994). “Diagnostic role of follicle-stimulating hormone (FSH) measurements during the menopausal transition–an analysis of FSH, oestradiol and inhibin”. Eur J Endocrinol. 130 (1): 38–42. doi:10.1530/eje.0.1300038. PMID 8124478.
- ↑ Visser JA, Schipper I, Laven JS, Themmen AP (2012). “Anti-Müllerian hormone: an ovarian reserve marker in primary ovarian insufficiency”. Nat Rev Endocrinol. 8 (6): 331–41. doi:10.1038/nrendo.2011.224. PMID 22231848.
- ↑ Torrealday S, Kodaman P, Pal L (2017). “Premature Ovarian Insufficiency – an update on recent advances in understanding and management”. F1000Res. 6: 2069. doi:10.12688/f1000research.11948.1. PMC 5710309. PMID 29225794.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Rahmah Al-Edresi, M.D.[2]