Mesangial proliferative glomerulonephritis
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Mesangial proliferative glomerulonephritis is a form of glomerulonephritis associated primarily with the mesangium.[1]
There is some evidence that interleukin-10 may inhibit it in an animal model.[2]
It is classified as type II lupus nephritis by the WHO.
References
- ↑ “Definition: mesangial proliferative glomerulonephritis from Online Medical Dictionary”.
- ↑ Kitching AR, Katerelos M, Mudge SJ, Tipping PG, Power DA, Holdsworth SR (2002). “Interleukin-10 inhibits experimental mesangial proliferative glomerulonephritis”. Clin. Exp. Immunol. 128 (1): 36–43. PMC 1906377. PMID 11982588. Unknown parameter
|month=ignored (help)
Historical Perspective
Please help WikiDoc by adding content here. It’s easy! Click here to learn about editing.
References
Classification
Please help WikiDoc by adding content here. It’s easy! Click here to learn about editing.
References
Pathophysiology
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overveiw
Pathophysiology
Mesangial cells in the renal glomerulus use endocytosis to take up and degrade circulating immunoglobulin. This normal process stimulates mesangial cell proliferation and matrix deposition. Therefore, during times of elevated circulating immunoglobulin (i.e. lupus and IgA nephropathy) one would expect to see an increased number of mesangial cells and matrix in the glomerulus. This is characteristic of nephritic syndromes.
References
Differentiating Mesangial proliferative glomerulonephritis from other Diseases
Please help WikiDoc by adding content here. It’s easy! Click here to learn about editing.
References
Epidemiology and Demographics
Please help WikiDoc by adding content here. It’s easy! Click here to learn about editing.
References
Risk Factors
Please help WikiDoc by adding content here. It’s easy! Click here to learn about editing.
References
Screening
Please help WikiDoc by adding content here. It’s easy! Click here to learn about editing.
References
Natural History, Complications and Prognosis
Please help WikiDoc by adding content here. It’s easy! Click here to learn about editing.
References
Diagnosis
Diagnosis
History and Symptoms | Physical Examination | Laboratory Findings | CT | MRI | Ultrasound | Other Imaging Findings | Other Diagnostic Studies
Treatment
Treatment
Medical Therapy | Secondary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies
Looking for the patient version?
© 2026 MyEClinic – IFTM Institut für Telematik in der Medizin GmbH