Effective measures to prevent recurrence of mesenteric ischemia include screening by duplex ultrasonography, nutritional and life style modification, and drug therapy.

The secondary prevention of mesenteric ischemia is similar to its primary prevention.

Effective measures for the secondary prevention of mesenteric ischemia includes the following:^[1][2][3][4]

• In patients with history of mesenteric ischemia, duplex ultrasonography is recommended after every 6 months for one year, and yearly thereafter.
• All patients at risk of developing mesenteric ischemia, should be educated about the signs and symptoms of the disease.
• Patients who undergo endovascular repair for mesenteric ischemia should be recommended the following:
  • Lifelong aspirin and statin therapy
  • Clopidogrel for 1-3 months after the procedure
  • Lifelong oral anticoagulants in case of persistent atrial fibrillation, mesenetric venous thrombosis and inherited or acquired thrombophilias.
  • Nutritional status and body weight should be monitored

• In cases of mesenteric venous thrombosis, the causes of hypercoaguability should be treated.