Mesial temporal sclerosis
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Overview
Mesial temporal sclerosis is a specific pattern of hippocampal neuron cell loss[1] [2]. There are 3 specific patterns of cell loss; Cell loss might involve sectors CA1 and CA4, CA4 alone, or CA1 to CA4 [3]. Associated hippocampal atrophy and gliosis is common[4]. MRI scan commonly displays increased T2 signal and hippocampal atrophy [5] Mesial temporal sclerosis might occur with other temporal lobe abnormalities (dual pathology) [6]. Mesial temporal sclerosis is the most common pathological abnormality in temporal lobe epilepsy[7] [8].
Patient #1: Asymmetry of the mesial temporal lobes is consistent with left mesial temporal sclerosis
References
References
- ↑ Bronen RA, Fulbright RK, Spencer DD, et al. 1997
- ↑ Trepeta, Scott 2007
- ↑ Trepeta, Scott 2007
- ↑ Bronen RA, Fulbright RK, Spencer DD, et al. 1997
- ↑ Bronen RA, Fulbright RK, Spencer DD, et al. 1997
- ↑ Bronen RA, Fulbright RK, Spencer DD, et al. 1997
- ↑ Bronen RA, Fulbright RK, Spencer DD, et al. 1997
- ↑ Trepeta, Scott 2007
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