Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Methoxyphenamine
Introduction
Overview
Overview
Methoxyphenamine (trade names ASMI, Euspirol, Orthoxine, Ortodrinex, Proasma), also known as 2-methoxy–N–methylamphetamine (OMMA), is a β-adrenergic receptor agonist of the amphetamine class used as a bronchodilator.[1]
Chemistry
Chemistry
Methoxyphenamine was first synthesized at the Upjohn company by Woodruff and co-workers.[2] A later synthesis by Heinzelman, from the same company, corrects the m.p. given for methoxyphenamine hydrochloride in the earlier paper, and describes an improved synthetic procedure, as well as resolution of the racemic methoxyphenamine.[3]
References
References
- ↑ Swiss Pharmaceutical Society (2000). Index Nominum 2000: International Drug Directory (Book with CD-ROM). Boca Raton: Medpharm Scientific Publishers. ISBN 3-88763-075-0.
- ↑ E. H. Woodruff, J. P. Lambooy and W. E. Burt (1940). “Physiologically active amines. III. Secondary and tertiary β-phenylpropylamines and β-phenylisopropylamines.” J. Am. Chem. Soc. 62 922-924.
- ↑ R. V. Heinzelman (1953). “Physiologically active secondary amines. β-(o-Methoxyphenyl)-isopropyl-N-methylamine and related compounds.” J. Am. Chem. Soc. 75 921-925.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]