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Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.

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Methyl isothiocyanate

Introduction

Space-filling model of methylisothiocyanate

Methyl isothiocyanate, CH3N=C=S, also known by the acronymn MITC, is a low melting (m.p. 31°C) colorless solid used in organic chemistry. It is a volatile (b.p. 117°C) lachrymator. Density 1.07 g cm–3. Its most characteristic reaction is with amines to to give methyl thioureas:

CH3NCS + R2NH → R2NC(S)NHCH3

MITC is used in agriculture as a soil fumigant. It is generated in situ from the reaction of metam sodium with water.

See also

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]