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Metisazone

Introduction

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Overview

Overview

Methisazone (USAN) or metisazone (INN) is an antiviral drug that works by inhibiting mRNA and protein synthesis, especially in pox viruses. It has been used in the past to treat smallpox.[1]

Methisazone has been described as being used in prophylaxis since at least 1965.[2][3]

References

References

  1. ↑ Methisazone, Merriam-Webster’s Medical Dictionary
  2. ↑ do Valle, LA; de Melo, PR; de Gomes, LF; ProenΓ§a, LM (13 Nov 1965). “Methisazone in prevention of variola minor among contacts”. Lancet. 2 (7420): 976–8. PMIDΒ 4159212.
  3. ↑ Weiss MM, Weiss PD, Mathisen G, Guze P (December 2004). “Rethinking smallpox”. Clin. Infect. Dis. 39 (11): 1668–73. doi:10.1086/425745. PMIDΒ 15578369.


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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]