Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Microangiopathic hemolytic anemia natural history, complications and prognosis
Introduction
- If left untreated, 90% of patients with [[[microangiopathic hemolytic anemia]] may die[1].
- The prognosis can be improved with prompt treatment. Therapeutic plasmapheresis reduces mortality rate to 20%[1].
- Common complications of microangiopathic hemolytic anemia include[2]:
- acute renal failure with raised serum urea and creatinine levels
- intracranial hemorrhage as a consequence of severe thrombocytopenia
- myocardial infarction due to coronary artery occlusion
Reference
- ↑ 1.0 1.1 Rock GA, Shumak KH, Buskard NA, Blanchette VS, Kelton JG, Nair RC; et al. (1991). “Comparison of plasma exchange with plasma infusion in the treatment of thrombotic thrombocytopenic purpura. Canadian Apheresis Study Group”. N Engl J Med. 325 (6): 393–7. doi:10.1056/NEJM199108083250604. PMID 2062330.
- ↑ Scully, Marie; Hunt, Beverley J.; Benjamin, Sylvia; Liesner, Ri; Rose, Peter; Peyvandi, Flora; Cheung, Betty; Machin, Samuel J. (2012). “Guidelines on the diagnosis and management of thrombotic thrombocytopenic purpura and other thrombotic microangiopathies”. British Journal of Haematology. 158 (3): 323–335. doi:10.1111/j.1365-2141.2012.09167.x. ISSN 0007-1048.