Microscopic polyangiitis epidemiology and demographics

The prevalence of Microscopic polyangiitis higher in Southern European countries and Asia.The incidence of GPA was similar to that of MPA.MPO‐ANCAs when positive in a patient was a marker of poor prognosis in the population of patients with AAV.

• The incidence of Microscopic polyangiitis is approximately 3.3 per 100,000 individuals worldwide.^[1]

• Microscopic polyangiitis in Europe is seen with higher incidences in Southern countries than in Northern countries. ^[2]

• The incidence of Microscopic polyangiitis is estimated to be 0.59 per 100,000 individuals per year in the United Kingdom.^[3]

• During the last two decades, the incidences of Microscopic polyangiitis has increased, which may be due to increased testing for various vasculitis as a result of availability of testing for ANCA.

• The prevalence of Microscopic polyangiitis is approximately 42.1 per 100,000 individuals worldwide.^[4]

• The incidence of Microscopic polyangiitis increases with age; the median age at diagnosis is 60 years.^[5]

• Males are more commonly affected with Microscopic polyangiitis than females (1.8:1).^[5]

• Microscopic polyangiitis tends to affect individuals of Asian and Southern European descent.^[6]

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