Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Minimal change disease risk factors
Introduction
Overview
Overview
The cause of minimal change disease has not been identified or idiopathic. Nephrotic syndrome is most commonly as a result of damage to the clusters of tiny blood vessels (glomeruli).But secondary causes may be due to Drugs, Toxins, Infection, and Tumor.
Common Causes
Common Causes
Common risk factors in the development of minimal change disease include:[1]
Common Risk Factors
- Children within the Age >1 year and <8 years
- Hodgkin lymphoma
- leukemia
- Recent viral illness
- Toxins such as Mercury, bee stings, fire coral exposure are one of the causes for minimal change disease.
- Medications such as:[2]
- Salazopyrin
- Mercury
- Tiopronin
- Lithium
- D-penicillamine
- Gold
- Tyrosine-kinase inhibitor
Less Common Causes
Less common causes of minimal change disease include:[3][4]
- Hepatitis B or HCV infection
- Low birth weight (LBW)
- Hematopoietic stem cell transplantation
References
References
- ↑ Iijima, Kazumoto; Hamahira, Kiyoshi; Tanaka, Ryojiro; Kobayashi, Akiko; Nozu, Kandai; Nakamura, Hajime; Yoshikawa, Norishige (2002). “Risk factors for cyclosporine-induced tubulointerstitial lesions in children with minimal change nephrotic syndrome”. Kidney International. 61 (5): 1801–1805. doi:10.1046/j.1523-1755.2002.00303.x. ISSN 0085-2538.
- ↑ Vivarelli M, Massella L, Ruggiero B, Emma F (February 2017). “Minimal Change Disease”. Clin J Am Soc Nephrol. 12 (2): 332–345. doi:10.2215/CJN.05000516. PMC 5293332. PMID 27940460.
- ↑ Vivarelli M, Massella L, Ruggiero B, Emma F (February 2017). “Minimal Change Disease”. Clin J Am Soc Nephrol. 12 (2): 332–345. doi:10.2215/CJN.05000516. PMC 5293332. PMID 27940460.
- ↑ Vivarelli, Marina; Massella, Laura; Ruggiero, Barbara; Emma, Francesco (2017). “Minimal Change Disease”. Clinical Journal of the American Society of Nephrology. 12 (2): 332–345. doi:10.2215/CJN.05000516. ISSN 1555-9041.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Vamsikrishna Gunnam M.B.B.S [2]