Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Mitochondrial myopathy
Introduction
Overview
Mitochondrial myopathy are a type of myopathy associated with mitochondrial disease.
Examples include:
- varying degrees of cognitive impairment and dementia
- lactic acidosis
- strokes
- transient ischemic attacks
- hearing loss
- dysmotility
- weight loss
- progressive myoclonic epilepsy
- clumps of diseased mitochondria accumulate in the subsarcolemmal region of the muscle fiber and appear as “ragged-red fibers” when muscle is stained with modified Gomori trichrome stain
- short stature
Kearns-Sayre syndrome (KSS)
- external ophthalmoplegia
- cardiac conduction defects
- sensory-neural hearing loss
- progressive ophthalmoparesis is the cardinal feature
- symptomatic overlap with many other mitochondrial myopathies
Template:PNS diseases of the nervous system Template:Mitochondrial diseases
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]