Mitral regurgitation (MR) can be classified as either acute or chronic according to the acuity of the events leading to the valvular abnormality. Chronic MR is further classified as primary or secondary based on the presence or absence of one or more abnormalities in the structures of the valves, respectively. Secondary MR can be either ischemic or functional.

• Mitral regurgitation (MR) can be classified as either acute or chronic according to the acuity of the events leading to the valvular abnormality.
• Chronic MR is further classified as primary or secondary based on the presence or absence of one or more abnormalities in the structures of the valves, respectively.
• Secondary MR can be either ischemic or functional.^[1][2][3][4]

  Mitral Regurgitation (MR)

  Acute MR

  Chronic MR

  Primary MR Due to the disruption of at least one of the valvular structures as a result of any of the following: Mitral valve prolapse Myxomatous degeneration (young patients) Fibroelastic deficiency disease (old patients) Infective endocarditis Connective tissue disease Rheumatic heart disease Radiation heart disease

  Secondary MR Due to a functional abnormality with a preserved normal structure of the mitral valve as a result of left ventricular dysfunction as seen in: Coronary artery disease (ischemic MR) Any condition leading to left ventricular dysfunction (functional MR)

  References

  1. ↑ Ciarka A, Van de Veire N (2011). “Secondary mitral regurgitation: pathophysiology, diagnosis, and treatment”. Heart. 97 (12): 1012–23. doi:10.1136/hrt.2010.219170. PMID 21586426.
  2. ↑ Nishimura RA, Otto CM, Bonow RO, Carabello BA, Erwin JP, Guyton RA; et al. (2014). “2014 AHA/ACC Guideline for the Management of Patients With Valvular Heart Disease: executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines”. Circulation. 129 (23): 2440–92. doi:10.1161/CIR.0000000000000029. PMID 24589852.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
  3. ↑ Ciarka A, Van de Veire N (2011). “Secondary mitral regurgitation: pathophysiology, diagnosis, and treatment”. Heart. 97 (12): 1012–23. doi:10.1136/hrt.2010.219170. PMID 21586426.
  4. ↑ Nishimura RA, Otto CM, Bonow RO, Carabello BA, Erwin JP, Guyton RA; et al. (2014). “2014 AHA/ACC Guideline for the Management of Patients With Valvular Heart Disease: executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines”. Circulation. 129 (23): 2440–92. doi:10.1161/CIR.0000000000000029. PMID 24589852.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)

  
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