Mitral valve prolapse history and symptoms

While mitral valve prolapse has been associated with a variety of symptoms it should be noted that the frequency of these symptoms does not differ significantly from that of the general population. Therefore the causal link between mitral valve prolapse and these associated symptoms is not clear. Some patients with MVP experience heart palpitations, atrial fibrillation, or syncope. Between 11% and 15% of patients experience moderate chest pain and shortness of breath. These symptoms may not be directly attributable to the prolapsing mitral valve, but rather by the mitral regurgitation that often results from prolapse. In addition, the American Heart Association has linked anxiety and panic attack disorders to Mitral Valve Prolapse, although the causal nature of this association is not clear.

For unknown reasons, MVP patients tend to have a low body mass index (BMI) and are typically leaner than individuals without MVP. MVP occurs more frequently among individuals with the Marfan syndrome.^[1]

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