Mixed connective tissue disease historical perspective
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shaghayegh Habibi, M.D.[2]
Overview
Overview
In 1972, Gordon C.Sharp was the first physician who defined MCTD. It has been the first rheumatic disease syndrome that has represented by a serologic test. In 1976, Alarcon-Segovia proposed criteria for MCTD classifying between all types of connective tissue diseases. It represents the close association between MCTD and Sjogren’s syndrome.
Historical Perspective
Historical Perspective
- In 1972, Gordon C.Sharp was the first physician who defined MCTD.
- MCTD has been the first rheumatic disease syndrome that has represented by a serologic test (positive U1RNP).[1][2]
- In 1976, Alarcon-Segovia proposed criteria for MCTD classifying between all types of connective tissue diseases. It represents the close association between MCTD and Sjogren’s syndrome.
- In 1987, Sharp, Alarcon-Segovia and The Research Committee of Japanese Ministry of Health and Welfare for MCTD (JMHW) suggested three groups of criteria for diagnosing MCTD.[3]
References
References
- ↑ Vij M, Agrawal V, Jain M (July 2014). “Scleroderma renal crisis in a case of mixed connective tissue disease”. Saudi J Kidney Dis Transpl. 25 (4): 844–8. PMID 24969199.
- ↑ Hoffman RW, Maldonado ME (July 2008). “Immune pathogenesis of Mixed Connective Tissue Disease: a short analytical review”. Clin. Immunol. 128 (1): 8–17. doi:10.1016/j.clim.2008.03.461. PMID 18439877.
- ↑ Alarcón-Segovia D (October 1984). “Symptomatic Sjögren’s syndrome in mixed connective tissue disease”. J. Rheumatol. 11 (5): 582–3. PMID 6512789.
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