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Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.

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Molluscum contagiosum historical perspective

Introduction

Overview

Overview

Molluscum contagiosum was first described by Bateman in 1817 in the second edition of his synopsis. In 1841, Paterson demonstrated molluscum contagiosum’s infectious nature. The viral nature of the disease was demonstrated by Juliusberg in 1905.

Historical Perspective

Historical Perspective

Discovery

Molluscum contagiosum was first discovered by Bateman in 1817.[1]

Landmark Events in the Development of Treatment Strategies

  • Molluscum contagiosum was first discovered by Bateman in 1817 in his second edition of his synopsis.[1]
  • In 1841, Paterson demonstrated molluscum contagiosum infectious nature.
  • Also in 1841, Henderson-Paterson bodies (intracytoplasmic inclusion bodies, lobules containing hyalinized molluscum bodies) were described by scientists Henderson and Paterson.[2]
  • In 1905, the viral nature of the disease was demonstrated by Juliusberg.[3]
  • In 1997, Senkevich et al were the first who described molluscum contagiosum virus (MCV) genome.[4]
  • Molluscum contagiosum virus types I-IV were identified with the advance of the technology through restrictive endonuclease analysis of the genomes of isolates.[5]
References

References

  1. ↑ 1.0 1.1 Pickering WR, Woods RA (1972). “The uptake and incorporation of purines by wild-type Saccharomyces cerevisiae and a mutant resistant to 4-aminopyrazolo (3,4-d) pyrimidine”. Biochim. Biophys. Acta. 264 (1): 45–58. PMID 4336666.
  2. ↑ Torres A (1986). “The molluscum body. The Henderson-Paterson body with Lipschütz granules”. Am J Dermatopathol. 8 (3): 260–2. PMID 3524303.
  3. ↑ RAKE G, BLANK H (1950). “The relationship of host and virus in molluscum contagiosum”. J. Invest. Dermatol. 15 (2): 81–93. PMID 15437050.
  4. ↑ Senkevich TG, Koonin EV, Bugert JJ, Darai G, Moss B (1997). “The genome of molluscum contagiosum virus: analysis and comparison with other poxviruses”. Virology. 233 (1): 19–42. doi:10.1006/viro.1997.8607. PMID 9201214.
  5. ↑ “www.microbiologyresearch.org” (PDF).

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mahshid Mir, M.D. [2]