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Health Dictionary

Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.

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Morning glory disc anomaly

Introduction

Overview

Overview

The morning glory disc anomaly (MGDA) is a congenital deformity resulting from failure of the optic nerve to completely form in utero.[1] The term was coined in 1970 by Kindler, noting a resemblance of the malformed optic nerve to the morning glory flower.[2] The condition is usually unilateral.[3]

On fundoscopic examination, there are three principal findings comprising the anomaly:[4]

  1. an enlarged, funnel-shaped excavation in optic disc
  2. an annulus or ring of chorioretinal pigmentary changes surrounding the optic disc excavation
  3. a central glial tuft overlying the optic disc
Associated conditions

Associated conditions

Although the finding itself is rare, MGDA can be associated with midline cranial defects and abnormal carotid circulation, such as carotid stenosis/aplasia or progressive vascular obstruction with collateralization (also known as Moya moya).[5] The vascular defects may lead to ischemia, stroke, or seizures and so a finding of MGDA should be further investigated radiographic imaging.

Complications

Complications

Serous retinal detachment can occur in the affected eye.[5]


See also

References

References

  1. ↑ Magrath, GN; Cheeseman EW; Sarrica RA (2013). “Morning Glory Disc Anomaly”. Pediatric Neurology. 49 (6): 517. doi:10.1016/j.pediatrneurol.2013.05.015.
  2. ↑ Kindler (1970). “Morning glory syndrome: unusual congenital optic disk anomaly”. Am J Ophthalmol. 69: 376–84.
  3. ↑ Barnard, Simon. “An Introduction to Diseases of the Optic nerve”. Retrieved 30 May 2014.
  4. ↑ Auber, AE; O’Hara M (1999). “,Morning glory syndrome. MR imaging”. Clin Imaging. 23: 152–158. doi:10.1016/s0899-7071(99)00118-7.
  5. ↑ 5.0 5.1 Quah, BL; Hamilton J; Blaser S; et al. (2005). “Morning glory disc anomaly, midline cranial defects and abnormal carotid circulation: an association worth looking for”. Pediatr Radiol. 35: 525–528. doi:10.1007/s00247-004-1345-y.

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Jyostna Chouturi, M.B.B.S [2]