Mucoepidermoid carcinoma medical therapy

There is no medical treatment for mucoepidermoid carcinoma. Radiotherapy can be neoadjuvant treatment in some lesions (dependent on the tumor stage and size).

There is no medical treatment for mucoepidermoid carcinoma, However chemotherapy can be used in order to shrink down the tumor. Chemotherapy can be the option for palliative care. Following agents can be used: Radiotherapy can be neoadjuvant treatment in some lesions (dependent on the tumor stage and size).^[1][1]

• • Doxorubicin
  • Mitoxantrone
  • Vinorelbine,
  • A new form of 5-fluorouracil called fluoropyrimidine
• Newer combinations with antimicrotubule agents such as cisplatin has shown some efficacy in malignant tumors.
• Paclitaxel has demonstrated moderate activity against mucoepidermoid tumors and adenocarcinomas but no effect adenoid cystic carcinoma.^[2]

• Various biological agents under investigation are:
  • Trastuzumab
  • Imatinib
  • Cetuximab

Radiotherapy can be used alone in non resecatable tumors as well as adjuvant therapy after surgery and chemotherapy. Various techniques using radiotherapy has demonstrated significant efficiacy in treatment of salivary gland tumors:

• • Gamma-knife stereotactic radiosurgery
  • Brachytherapy
  • Iodine-125
  • Proton based radiation
  • Neutron therapy^[3]

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