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Multi-drug-resistant tuberculosis MRI

Introduction

Overwiew

Overwiew

MRI is used for the assessment of extrapulmonary tuberculosis, such as CNS tuberculosis, osteoarticular tuberculosis, Pott’s disease, and parotid gland tuberculosis.

MRI

MRI

CNS Tuberculosis

  • MRI is most commonly used in cases of CNS infection with tuberculosis.
  • The following findings may be seen in CNS tuberculosis:[1]
  • Ring-enhancing mass in T2 and hypodense lesion in case of a non-caseating tuberculoma.
  • A caseating tuberculoma is seen as a hypodense lesion in both T1 and T2.
  • Cerebral edema
  • Diffuse enhancement in case of meningitis
CNS Tuberculoma
Image courtesy of Dr Praveen Jha, Radiopedia. (original file here) Creative Commons BY-SA-NC
CNS Tuberculoma
Image courtesy of Dr Praveen Jha, Radiopedia. (original file here) Creative Commons BY-SA-NC

Pott’s Disease

  • Spinal MRI is the image diagnostic test of choice for spinal tuberculosis.
  • Findings include: [2]
  • Endplate irregularity
  • Irregular anterior aspect of the vertebral bodies
  • Edema and enhancement of the bone marrow.
  • Destruction of vertebral body in severe cases.
Spinal Tuberculosis C6-C7
Image courtesy of Dr Hani Salam, Radiopedia. (original file here) Creative Commons BY-SA-NC
Spinal Tuberculosis C6-C7
Image courtesy of Dr Hani Salam, Radiopedia. (original file here) Creative Commons BY-SA-NC
Spinal Tuberculosis C6-C7
Image courtesy of Dr Hani Salam, Radiopedia. (original file here) Creative Commons BY-SA-NC

Osteoarticular Tuberculosis

  • MRI findings in osteoarticular tuberculosis include:[3]
  • Demineralization
  • Narrowing of the joint space
  • Bone and cartilage erosion
  • Calcifications

Parotid Gland Tuberculosis

  • Tuberculosis infection of the parotid gland con mimic a parotid neoplasm.
  • The MRI shown below reveals a well-defined mass lesion, measuring 16 Γ— 21 Γ— 30 mm in size, hypointense on T1-weighted images, and hyperintense on T2-weighted images with homogenous contrast enhancement, located in the posterior part of the superficial lobe of the right parotid gland.[4]
Image courtesy of Wikimedia Commons.
References

References

  1. ↑ Burrill, Joshua; Williams, Christopher J.; Bain, Gillian; Conder, Gabriel; Hine, Andrew L.; Misra, Rakesh R. (2007). “Tuberculosis: A Radiologic Review1”. RadioGraphics. 27 (5): 1255–1273. doi:10.1148/rg.275065176. ISSNΒ 0271-5333.
  2. ↑ Torres C, Riascos R, Figueroa R, Gupta RK (2014). “Central nervous system tuberculosis”. Top Magn Reson Imaging. 23 (3): 173–89. doi:10.1097/RMR.0000000000000023. PMIDΒ 24887691.
  3. ↑ GrubisiΔ‡ F, BoriΔ‡ I, Segota A, Kruslin B, Grazio S (2014). “An unusual manifestation of osteoarticular tuberculosis: case report”. Acta Clin Croat. 53 (2): 237–41. PMIDΒ 25163241.
  4. ↑ Birkent, Hakan; Karahatay, Serdar; Akcam, Timur; Durmaz, Abdullah; Ongoru, Onder (2008). “Primary parotid tuberculosis mimicking parotid neoplasm: a case report”. Journal of Medical Case Reports. 2 (1): 62. doi:10.1186/1752-1947-2-62. ISSNΒ 1752-1947.

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Alejandro Lemor, M.D. [2]