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Multi-drug-resistant tuberculosis risk factors

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Alejandro Lemor, M.D. [2]

Overview

Overview

Risk factors for multi-drug resistant tuberculosis include exposure to an individual with MDR-TB, previous TB treatment, HIV infection, and a low socioeconomic status.

Risk Factors

Risk Factors

  • The risk factor for developing multi-drug resistant tuberculosis include:[1][2][3]
  • Exposure to a patient with MDR-TB
  • Previous TB treatment
  • HIV infection
  • Previous incarceration
  • Failed TB treatment
  • Relapse following standard TB treatment
  • Low income and low socioeconomic class
  • Individuals that come from areas of the world where drug-resistant TB is common
  • Individuals that have spent time with someone known to have drug-resistant TB disease
  • Adverse reactions of the drugs used in the treatment of tuberculosis contribute to the cease of the drug regimen and increases the probability of multi-drug resistance.
  • Direct observed treatment plays an important role to avoid drop-outs from tuberculosis medical regimen, which is an important risk factor for developing resistance to the standard medical regimen.


References

References

  1. Z. Mor, D. Goldblatt, H. Kaidar-Shwartz, N. Cedar, E. Rorman & D. Chemtob (2014). “Drug-resistant tuberculosis in Israel: risk factors and treatment outcomes”. The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease. 18 (10): 1195–1201. doi:10.5588/ijtld.14.0192. PMID 25216833. Unknown parameter |month= ignored (help)
  2. Mahfuza Rifat, Abul Hasnat Milton, John Hall, Christopher Oldmeadow, Md Akramul Islam, Ashaque Husain, Md Wahiduzzaman Akhanda & Bodrun Naher Siddiquea (2014). “Development of multidrug resistant tuberculosis in bangladesh: a case-control study on risk factors”. PloS one. 9 (8): e105214. doi:10.1371/journal.pone.0105214. PMID 25136966.
  3. “Multidrug-resistant tuberculosis”.

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