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Mycobacterium avium complex infection

Introduction

Overview

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References

Historical Perspective

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Classification

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Pathophysiology

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Overview

Pathophysiology

Etiologic Agent:

Mycobacterium avium complex (comprising M. avium and M.intracellulare).

Transmission:

Although the mode of transmission is unclear, MAC is most likely environmentally acquired.

References

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Causes

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References

Differentiating Mycobacterium avium complex infection from other Diseases

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Epidemiology and Demographics

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Overview

Epidemiology and Demographics

Not reportable. Population-based data available for Houston and Atlanta metropolitan areas suggest a rate of 1/100,000/year. Incidence is decreasing among HIV- infected patients as a result of new treatment modalities e.g., combination therapy with nucleoside reverse transcriptase inhibitors and protease inhibitors, as well as antimycobacterial prophylaxis. Incidence is decreasing because of changes in treatment for HIV-infected patients; however, antimicrobial resistance may be increasing.

References

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Risk Factors

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Risk Factors

HIV-infected persons. Rarely in children or nonimmuno-compromised persons.

References

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Natural History, Complications and Prognosis

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References

Diagnosis

Diagnosis

History and Symptoms | Physical Examination | Laboratory Findings | Chest X Ray | CT | MRI | Echocardiography or Ultrasound | Other Imaging Findings | Other Diagnostic Studies

Treatment

Treatment

Medical Therapy | Primary Prevention | Secondary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies

Case Studies

Case Studies

Case #1

Acknowledgements

Acknowledgements

The content on this page was first contributed by: C. Michael Gibson, M.S., M.D. Template:SIB

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]