Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Mycobacterium cookii
Introduction
Mycobacterium cookii
Description
Description
Gram-positive, nonmotile and polymorphic acid-fast rods (0.8µm x 1.4µm – 1.9µm). Forms clumps, but not cords or cross bands. Does not form spores, capsules and aerial hyphae.
Colony characteristics
- Colonies are smooth and glistening with yellow-orange pigmentation (0.5–1.0 mm diameter, scotochromogenic).
Physiology
- Slow growth on Löwenstein-Jensen medium or Middlebrook 7H10 agar at 31°C (optimal temperature). No growth at 37°C, 42°C or 45°C.
- Most of the strains are susceptible to ethambutol, isoniazid, streptomycin, and rifampin.
Differential characteristics
- Phylogenetic position between the slowly growing pathogenic species and the saprophytic rapidly growing species by partial 16S rDNA sequencing.
Pathogenesis
Pathogenesis
- Not pathogenic for humans, mice, guinea pigs and rabbits. Biosafety level 1.
- Provokes a non-specific hypersensitivity reaction to bovine tuberculin.
Type Strain
Type Strain
Strain NZ2 = ATCC 49103 = CIP 105396 = DSM 43922 = JCM 12404.
References
References
- Kazda et al. 1990. Mycobacterium cookii sp. nov. Int. J. Syst. Bacteriol.,40, 217-223.
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