Mycobacterium goodii

Gram-positive, nonmotile and acid-fast rods.

Colony characteristics

• Smooth to mucoid, off-white to cream coloured colonies. Yellow to orange pigment produced in 78% of all strains, after 10-14 days incubation.

Physiology

• Rapid growth on Middlebrook 7H10 and trypticase soy agar at 30°C, 35°C and 45°C within 2-4 days.
• Susceptible to amikacin, ethambutol, sulfamethoxazole.
• Intermediate susceptible to ciprofloxacin, doxycycline and tobramycin.
• Variable susceptible to cefmetazole, cefoxitin and clarithromycin.
• Resistant to isoniazid and rifampicin.

Differential characteristics

• Comparable clinical settings to M. smegmatis and members of the M. fortuitum complex.

• Production of post-traumatic wound infections especially those following open fractures and with associated osteomyelitis and chronic lipoid pneumonia.

First isolated from a patient with a post-traumatic osteomyelitis of the heel(USA). Strain MO69 = ATCC 700504 = CIP 106349 = DSM 44492 = JCM 12689. Mycobacterium goodii was previously known as Mycobacterium smegmatis group 2.

• Brown et al. 1999. Mycobacterium wolinskyi sp. nov. and Mycobacterium goodii sp. nov., two new rapidly growing species related to Mycobacterium smegmatis and associated with human wound infections: a cooperative study from the International Working Group on Mycobacterial Taxonomy. Int. J. Syst. Bacteriol., 1999, 49, 1493-1511.

de:Mycobacterium goodii nl:Mycobacterium goodii

Template:SIB

Template:WikiDoc Sources