Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Mycobacterium gordonae
Introduction
Mycobacterium gordonae
Description
Description
Gram-positive, nonmotile and moderate to long acid-fast rods.
- Commonly found in tap water and soil. Casual resident in human sputum and gastric lavage specimens.
Colony characteristics
- Smooth, with yellow or orange scotochromogenic colonies. Even though they are scotochromogenic pigment is intensified by growing in continuous light.
Physiology
- Growth on Löwenstein-Jensen medium and Middlebrook 7H10 agar within 7 or more days at 37°C (optimal 25°C).
- Does not grow in the presence of ethambutol (1mg/l), isoniazid (10mg/l) and sodium chloride (5%).
Differential characteristics
- A commercial hybridisation assay (AccuProbe) to identify M. gordonae exists.
- Intraspecies variability in 16S rDNA sequences
Pathogenesis
Pathogenesis
- Rarely if ever implicated in disease processes unless patients are immunocompromised.
- Biosafety level 1
Type Strain
Type Strain
Strain ATCC 14470 = CCUG 21801 = CCUG 21811 = CIP 104529 = DSM 44160 = JCM 6382 = NCTC 10267.
Treatment
Treatment
Antimicrobial regimen
- M. gordonae [1]
- Preferred regimen: Ethambutol OR Rifabutin OR Clarithromycin OR Linezolid OR Fluoroquinolones
References
References
- ↑ Griffith, David E.; Aksamit, Timothy; Brown-Elliott, Barbara A.; Catanzaro, Antonino; Daley, Charles; Gordin, Fred; Holland, Steven M.; Horsburgh, Robert; Huitt, Gwen; Iademarco, Michael F.; Iseman, Michael; Olivier, Kenneth; Ruoss, Stephen; von Reyn, C. Fordham; Wallace, Richard J.; Winthrop, Kevin; ATS Mycobacterial Diseases Subcommittee; American Thoracic Society; Infectious Disease Society of America (2007-02-15). “An official ATS/IDSA statement: diagnosis, treatment, and prevention of nontuberculous mycobacterial diseases”. American Journal of Respiratory and Critical Care Medicine. 175 (4): 367–416. doi:10.1164/rccm.200604-571ST. ISSN 1073-449X. PMID 17277290.
- Bojalil et al. 1962. Adansonian classification of mycobacteria. Journal of General Microbiology, 28, 333-346.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]